200+ Pet Friendly Hotels and Vacation Rentals in South Main |
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South Main Pet Friendly Vacation Rentals

About South Main Vacation Rentals

There are more than 200 places to stay in South Main and many that are available that welcome pets. These options include dog-friendly hotels, resorts, rentals as well as short-term private accommodations (i.e. RVs, Condos, Cabins, Chalets, etc.). The places can provide you with a great option on your next holiday. Compare many pet-friendly places to stay in South Main.

Are you seeking a last-minute pets-allowed hotel deal, or are you wanting to find the best deals available for hotels, resorts, cottages, condos, private villas, chalets, or a large vacation homes? With PetFriendly South Main, you can quickly compare different options to find the hottest deals with a single click. Looking for pet travel at a resort with an infinity pool, hot tub, is pet-friendly, or features a large master suite bedrooms or has a fireplace? You can find hotels, resorts, or other popular Airbnb-style properties in or near South Main. Places to stay near South Main are 456.08 ft² on average, with prices averaging US $151 a night.

PetFriendly makes it easy to find and compare hotels, resorts, and holiday rentals in South Main with prices often listed at a 30-40% off the rack rate. Just enter your destination and secure your pet-friendly place to stay today.

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Top Dog Hotels, Pet-Friendly Vacation Rentals, and Places to Stay in South Main

Type Count
Holiday Apartments 131
Vacation Homes 34

Use these Quick Filters to Find a Vacation Rental in South Main

★ Pro Tip: PetFriendly™ has the best results when it comes to finding places to stay that accept pets anywhere around the world. Travelers can find and compare over 10 million listings from all over the world. Use the intelligent Filter feature to compare homes, hotels, vacation rentals, bed and breakfasts, private Airbnb-style rentals, eco-friendly properties, inns, resorts, and more. Enjoy Pet Travel without Hassle in South Main.

Weather in South Main, TX

View the weather forecast for South Main before booking your hotel or rental.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Stay Near South Main, TX

PetFriendly finds and compares Pet-Friendly hotels, rentals, and resort listings near many of South Main's attractions.


Toyota Center
MD Anderson Cancer Center
NRG Stadium
Minute Maid Park
George R. Brown Convention Center
Houston Zoo
NRG Park
University of Houston
CityCentre
Downtown Aquarium
Rice University
Houston Museum District
Houston Natural Science Museum
Discovery Green
Memorial City Mall
Smart FiNonecial Centre at Sugar Land
Children's Museum of Houston
House of Blues Houston
Memorial Park
Revention Music Center

Frequently Asked Questions About South Main?

What are the top vacation rentals in South Main?

Find the best options in or near South Main for pet-friendly travel. If you are planning a trip or vacation in South Main, consider a week or two at exciting pets-allowed hotels, resorts, or other suggested properties best known as Top Vacation Rentals and Places to Stay in South Main:

How many PetFriendly vacation rentals are available in South Main?

PetFriendly™ updates its properties regularly to bring you a great selection of places to stay with their pet policies clearly spelled out. At present, the total number of active properties listed by PetFriendly in 2025 is over 200 in the South Main area, and still growing every day. When we combine listings from multiple websites and travel providers, PetFriendly can provide you with a huge selection of the best places to stay that welcome pets in South Main.

Nearby Neighborhood (2) 
Neighborhood Property Count
Texas Medical Center Pet Friendly Hotels and Vacation Rentals in Houston, Texas 389
Astrodome Pet Friendly Hotels and Vacation Rentals in Houston, Texas 213

People Also Ask

There are 200 South Main, TX Vacation Rentals

Recently Booked Pet Friendly Hotels and Vacation Rentals in South Main